|SOTD||Staff of the dead|
|SSC||Stronghold Slayer Cave|
|Safer||Someone who heals at a life points value that is greater than the maximum hit of the opponent or in some cases eating to full Hitpoints. Typically used in the context of one-on-one PvP. Although, some use it in multi-way combat incorrectly.|
|Scimmy, Skimmy, Scim, Skim||Scimitar|
|Skiller||Someone who trains non-combat skills (can be any Combat level)/more commonly someone who trains non-combat skills primarily or exclusively. See Skill pure.|
|Snipe||To receive a desirable drop in LootShare in RS3, when one does not have the highest LootShare potential in the team.
To target and gain a desirable item by outbidding or beating another player to it. See Sniping.
|SOS/Stronghold||Stronghold of Security|
|Spec (SS)||Spectral spirit shield|
|SS||Saradomin sword, screenshot|
|Super sets (Sup att/atk, Sup def, Sup str)||Super attack potion, Super defence potion, Super strength potion|
|Sword||Swordfish, Sword, or Longsword|